Evening, I am certainly not going to defend the 15-50 at all. However, in general - you are going to suffer the reverse of what I went through. You are starting rather long and then going wider. In this respect you are going to suffer some "lack of sharpness", just due to the enlarging of the angle of view of the lens, along with going from a prime to a zoom.
The sensor size is going to remain constant (it does not change size, resolution or density when you change lenses), and the 100mm lens has a field of view of 16 degrees. In comparison, the 16-50 has a field of view that ranges from 83 to 31 degrees wide (in width). What that means is that each pixel at 50mm will be representing at least four times as much area when compared to the 100mm lens. Sharpness will degrade solely for this reason alone. This is just the law of optics. So you are going to need to factor this into your analysis of the lens.
Also, you are comparing a prime to a zoom. Just by the nature of the optical design, there are going to be compromises in the design of the zoom that the prime will not need to contend with. Very few zooms are able to match a prime in sharpness, especially a highly rated prime such as your 100mm.
The FA 31 is excellent. I also believe that the 43 is extremely sharp also. It would certainly be easier to compare a prime to a prime.