Thanks for the replies...
I'm thinking, whatever combo I get, that I have the Sigma 10-20 for ultra wides... however, I am seriously contemplating selling my sigma 10-20 and sigma 105/2.8 for whichever combo (though the 105 is my fave lens and its hard to let it go, I assume the IQ of the 50-135 and hopefully the 60-250 will more than make up for it. But I lose macro capabilities...).
@Buddha: Finances permitting, I think your gear list is just perfect!
16-135/2.8, with a 200/2.8 for longer reach, and two fantastic macro lenses! What's missing is the DA* 11-16 and your all set!
If only I had more clients to help me fund my LBA!