I'd say once set up, go all the way - shoot every aperture you've got. Any/everything you can do to take variables out like shake, e.g. by using remote, tripod, mirror lockup with delay, etc. will give you better info. And remember, you're trying to figure out what the lens is capable of, so even though you might go out with the monopod, the more you can do to make your test shots without variables, the better info you'll have about what the lens is capable of. I've found myself running the gamut on aperture and shutter speed while birding. Sometimes it's dimmer than you think, you need it wide open, and you can barely hold it steady enough. Then next thing you know, it'll be bright sun, and you need to stop it way down. Some lenses hold pretty consistent though the range of apertures, and others will really get crisp/go fuzzy at certain points. And each copy of a given lens will be different. Also, look at the results, and if they don't make sense, go shoot it again. I'm doing some comparisons of an SMC 15 Limited and an HD 15 Limited right now, and just did some shots that didn't make sense. Set everything up again, retook them, and the results the second time around made more sense. First batch with the HD 15 were too soft based on past experience. What did I do wrong? Not sure, but more tests will be done tomorrow sorting it out. Crazy? Perhaps, but if suffering from LBA, might as well get your money's worth.