If you're OK with the weight and bulk, go for it. I use a Sony Zeiss 24-70 f/2.8 on Sony full-frame gear, and it's a great lens (probably the best lens I own and use) - but it can be tiresome to have that weight of combo hanging around my neck for a large part of the day.
If you want something much lighter and the focal length range works for you, consider the Tamron 28-75 f/2.8. You'll see some mixed reviews, but I firmly believe that most of the negative reviews are from those who haven't taken time to carefully set up AF fine adjustment, or else need a wider field of view. I have two of these - one that I use on my APS-C Pentax bodies, the other on my Sony cameras. The AF fine tune is set up pretty much perfectly on both, and I'm very happy with IQ even wide open and at short range (where shallow DOF is unforgiving). Stopped down to f/4 or beyond, it's excellent. The out-of-focus rendering is also very good indeed. On APS-C, the field of view is equivalent to 42-112mm, which some would find limiting but I find excellent for general use - especially if I carry something like the DA21 with me for the wide end. No WR and, of course, it's screw-drive - but it's also inexpensive if you look around for deals.
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