Originally posted by Peter Zack Full stops are F1.4, F2.0, F2.8 and F4.0
So the FA 50mm is 2 stops faster with a very shallow DOF when wide open (a plus IMO for some situations) and the 50-135 is one stop faster which with a camera like the K20 or K-7 could be compensated much of the time by an ISO boost. But size and weight are going to be factors as Wheatfield says.
These are very different beasts and it's either size and length vs speed and shorter FL. You really have to determine which is most important for your shooting style.
My bad i thought he was talking bout differece of 50-135mm and 60-250mm