I just took this shot today, indoors with natural light through a nearby window. It's a house guest making friends with our pit bull terrier. I used a Pentax 50mm f/1.4 prime, set on aperture priority f/2.8; it went to 1/200 second and worked out to ISO 4000. I was really impressed with the quality of the pic at this high ISO. I bought the K-5 about a year ago specifically to take advantage of its high ISO capability, among other things. The picture was reduced with Photoshop elements 7, but is otherwise untouched. Whatcha think?
John