You can use the Space Travel Calculator here:
Space travel calculator
A one way trip to the newly discovered K-186f (about 500 light years) at a constant 1g acceleration:
Max velocity: 0.9999925404694808 C (speed of light)
Observer lapsed time: 501.93500061650957 years
Traveler lapsed time: 12.11634248427413 years
So you would need systems that have a run time life of at least 13 years as well as supplies for the same amount of time just for the trip. You can play with the numbers in the calculator to give a rough idea of what you are facing.
Of course you would need a propulsion system capable of a constant 1g acceleration in the first place.