No sooner than I hit the "enter" key that I remember that media size does matter in at least one case as pertains to amount of light available for the exposure.
There is a light fall-off related to the incident angle light striking the media. The fall-off is equivalent to cos^4 theta where theta is the angle between the center of the lens and a particular point on the media. With symmetrical wide angle lenses in large format photography, this is a serious concern and may result in a difference of 2-3 stops between center and edge of the lens image circle. This is different than vignette and cannot be addressed by optical design
per se. As a result, many large format wide angle lenses require a radial gradient neutral-density filter to provide compensation for the drop-off. These filters are very $$$ and are often a dedicated match to the lens in question.
With 4x5 film light fall-off becomes an issue at or near 90mm and gets worse as you go wider. The rear surface of a 65mm lens* on 4x5 is often less than a centimeter from the surface of the film for an image circle of about 17 cm. The angle of incidence is very shallow.
The same physics apply to the retrofocus lenses used on SLR cameras but the angles are steep enough to not be a problem. It certainly applies to ultra wide-angle rangefinder lenses and has been a topic of discussion in regards to Leica M lenses adapted to mirrorless cameras. See the paragraphs under "Center Filter" on the filter information page at largeformatphotography.info:
http://www.largeformatphotography.info/filters.html
Steve
* Equivalent to a 16mm symmetrical ultra-wide in Leica M mount