It all depends on what kind of shooting you do. If you usually shoot in good light or with flash, it's not a problem. Image stabilization gets you even farther nowadays.
But if you're going to do available light photography in areas where light is not available, high ISO is quite useful. Typically the very highest ISO setting on any given camera is useless for artistic imaging, but it's nice to know it's there. Down one stop is quite noisy and some loss of sharpness, but usable if needed. Two stops down is usually quite good. On my NEX-5N I find that ISO 6,400 to 12,800 and a Samyang 35/1.4 let me shoot in some quite dark areas without a flash, and I find this useful. A stabilized sensor would be even better for many subjects.
Obviously at that point you do get some noise. Typically applying chroma noise reduction will mostly fix the problem - it's still there but much less noticeable. Lumi noise reduction will reduce the leftover grain, but it also hurts sharpness. Typically though some grain doesn't look out-of-place for the shots where you are using those kind of settings though.
At this point it's pretty much a "gimme" in any sensor that's new within the last 5 years. There's nothing wrong with keeping that capability in your back pocket in case you need it.
Last edited by Paul MaudDib; 04-12-2016 at 08:59 AM.