maxxxx, I went through quite a bit of trial and error before finally figuring out a comfortable and accessible combination. A backpack with a hip belt really helps distribute the weight off your shoulders. If you are going on long hikes, the weight of gear, food, and water adds up. Keep my camera attached to the hip belt with a Peak Design Capture Clip:
https://peakdesignltd.com/store/capturepro
While it doesn't offer protection for the camera, I like it because I can have my camera ready very quickly. The quick release plate also fits on my tripod. When I need to protect the camera, scrambling up rocks, for example, I simply just pack it away in the backpack.
On the other side of the hip belt I've got a couple lens cases so I can effectively swap out three different lenses fairly quickly. I like that part because near the end of hikes when I'm pretty tired, the last thing I want to do is unbuckle everything, take the pack off, and rummage around for a different lens.
As for the tripod, usually just keep it propped up on my shoulder, but can also strap it to the backpack if I need my hands free. A lightweight tripod pays off.