Originally posted by MossyRocks I had thought that because of the substantially longer distance to the focal plane with the extension tubes that there would be an effect. I may be wrong and would welcome correction but it seems that in addition to magnifying the image we would also be magnifying the diffraction a comparable amount. So at 6:1 with my setup any diffraction would also be magnified 6x similar to using an f-stop 6x as great as the airy disk would have a diameter 6x the size on the sensor.
Yes, that's how it works, but see that in one case you're magnifying the diffraction, whereas in the other case you're effectively adding diffraction. That's why I talk about actual aperture and effective aperture, which is just adding exposure compensation to the f number. One could also add it to shutter speed or compensate with sensor/film sensitivity.
See, f/4 is still f/4 at any focal length, but it's magnification that determines how much is in focus. Close to infinity it tends to be pretty much infinite, but as you focus closer, DoF becomes exponentially smaller. And smaller focal lenghts magnify less, so that's why everything tends to be pretty much in focus.
OTOH some designs suffer less from vignetting and light falloff while focusing than others, like rangefinder or mirrorless vs. SLR retrofocus designs for smaller focal lenghts because of the rear element to sensor/film distance and thus a different proportion between focusing travel and that distance.
It's the opposite for telephoto vs. non-telephoto designs. And it gets more complicated for front, rear or internal group focusing lenses and zooms.