Originally posted by bkpix ... at the distance you're most interested in optimizing for...
A good point worth highlighting. Some zoom lenses require different adjustment at different focal lengths and for different subject distances. Most lenses work decently all around if you adjust for the middle of the zoom range and at a normal subject distance, but some need extra attention. I have one lens in particular that requires extra adjustment when the subject is within three feet, so I just dial it in when I know I need it.