I had a topic before on the name K3 III AF Adjustment anomalies and i think that the cause of all of this are the different AF Adjustment calibration needed for the outer AF Points and additionally the different calibration needed for the different zoom ranges of the zoom lenses.
So at the end i decided to give up calibrating for the center point. Yes i do the AF calibration for the center point but after that i take quite a few shots with different focus points and in different focus modes and take the one AF Adjustment setting which seems to be the best all rounder.
For example my 16-50 is sharpest on the long end with AF Adjustment value +5, but using overally in all range and especially with the AF auto area mode, it's giving the most satisfactory result with AF Adjustment +4 for most of the pictures.
To be honest with the old K3 i was never using the AF auto area modes while with the K3 III i tend to use it mostly. So calibrating only for the center point is quite useless. Maybe if Pentax could implement AF Adjustment for several AF points individually then we would have a perfect calibration.
And to be honest again, it's only pixel peeping as the machine is taking exceptionally good pictures and the focus is generally fast, good and accurate. Only if some are doing AF Adjustment then it's easy to fall in the trap of pixel peeping.