Welcome to PF!
After owning the DA* 50-135 for awhile (which I absolutely love) I sprung for the DA* 16-50 but I'm very unhappy with it. I'm sure it's just a poor copy but it put a bad taste in my mouth for this particular lens (which I can't return until I get home from my overseas travels). Plus, I just bought an FA 31mm limited and now the only time I use the 16-50 is if I need to shoot in nasty weather or need wide angle (until I get the 15mm anyway). The 31mm just destroys the 16-50 in IQ, sharpness, etc.
So, now that I've had these experiences, I'm heading down the prime path instead. I hope it's just an issue of getting a poor copy of the 16-50, but even still I feel like primes are the way to go (for me at least). To me, they're more fun and produce better quality photos.