Sorry it took me so long - a few projects popped up last minute at work and I didn't get home near midnight. But, as promised, here's my attempt. LR4 and Topaz DeNoise.
Straight Noise Reduction
Attachment 192158
NR with WB adjusted using the dropper in LR4 and using the (assumed white)
N264 text on the keyboard lower left as the 'white card'. I then used the spot brush in LR4 with
Noise Reduction +100 and
Sharpness -100 to smooth out the noise/artifacts of the background/screen. I also locally dropped the shadows a bit and
Clarity +10 on the brush as well.
Attachment 192160
Also, I would agree with the advice given above. It would be well worth it to invest in a relatively cheap prime 50mm lens. The difference between f/5.6 and an aperture of about f/2 would drop your ISO
dramatically. And in combination with that, if someone is just speaking, and not moving around a lot, I find that you can get away with 1/50s or even slower if you time it right (i.e. wait for a pause in their speech/movement). That would also drop your ISO considerably.
Hope this helps, and again, sorry for the delay in getting back to you.
-Heie