Originally posted by halfspin The name f/64 refers to the smallest lens opening on the camera through which light passes: images photographed at this setting yield sharp focus and fine detail of subject matter.
As an 8X10 photographer myself I rarely use f/64 - I prefer to use camera movements to extend DOF because at f/64 you can kiss resolution goodbye because of diffraction. Most large format lenses perform best at f/16~f/22*, so I tend to stick around that aperture and use tilt,rise, fall and swing to manipulate the DOF to cover my subject and still obtain superb image quality.
*and these days most Schneider and Rodenstock lenses perform just as well as most high performance 35mm primes do - it is possible to obtain resolution of exceeding 100lp/mm, that kind of detail spread over a large 8X10 negative is something to behold.