Kent, I also use a 1280, and have found that, if I let it sit unused for a few weeks, I occasionally have to run the cleaning routine a few times, with an hour or two lapse between attempts, before the plugged nozzle(s) will clear. The manual suggests that vertical lines are a result of head misalignment, but I haven't had that problem. Maybe it, too, would respond to repeated attempts spaced out over a few hours.
If that doesn't work, you might try downloading the current drivers and reinstalling them. I'd recommend logging out and back into your user account after doing so. Let us know what happens!
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