Originally posted by Rondec This is a night shot, not? I mean it is iso 800 shot at 13 seconds.
Good catch, I missed that when I first looked at it. I now see that aperture was f29, which explains the weird starburst pattern. Depending on how much digital fidgeting the OP wants to do, one shot could be taken to expose for the moon, one shot to expose for the foreground and then combine the two. Not blowing out the moon also means that the moonlit clouds will look much better and I don't think there is a single exposure setting that will allow for capturing enough detail from both the sky and the foreground.
At 53mm, this lens is wide open at f4.5, which will be good for depth of field and sharpness for everything except possibly the "ugly building in the foreground." A full moon is a pretty big light source and will dominate the image no matter what, so if the OP wants to avoid a composite image, then I would expose to get the moon looking like a moon at ISO 100 and use a mask to brighten up the foreground. Whatever foreground detail can be recovered is better than black.
Assuming that there won't be another opportunity to take the same picture, then my suggestion is to try making this photo darker, so the moon's starburst doesn't overpower the clouds so much and the outline of the foreground will still be visible.