Originally posted by D W I am sure someone will make it fit and work; whether it is the 500/5.6APO Mamiya or the 150-500 Sigma.
the sigma 150-500mm is a 35mm lens and would be essentially useless on a 645D. The mamiya 645 uses a flange that is substantially shorter* then the pentax 645's and it would require some alteration of the focus travel on the mamiya lens in order to get it to focus at infinity on the pentax. Adapting a lens designed for a shorter flange to a longer flange distance requires some expensive tools and it is highly probable the alterations will involve damaging the lens, rendering it useless on the system it was designed for. I know people who get really bent out of shape when anyone alters a pentax K mount lens to fit other systems, because it does involve removal of the aperture leaver and guard.
*mamiya 645= 63.3mm, Pentax 645= 70.87mm