Quote: Another take-away is that CoC is defined a bit too coarsely for the latest FF small pixel cameras like the D800. With such high resolution, you should set Depth of Field narrower than the aperture markings on the lens based on the older definition of CoC (whatever, something like 20/20 vision at 20 inches from a 20 inch print?)
Actually, the difference is about the definition and by extension the math and science, which is pretty clear. I don't think you understand the basic concept of permissible circles of confusion. The pixel size will have no impact on image sharpness. Neither will it have any effect on the diffraction limit nor DoF. Go back the the Cambridge Colour page and then go to their section on the DoF calculator for an explanation.
Take a sharp image with a pixel resolution of X. Then take the same image with the same format with a pixel resolution of 2x. Do you think the 2X image will be softer because it is divided into more pixels? The issue is how our eyes perceive an image. A 100% monitor view is not a real world viewing condition and image sharpness in terms of diffraction limit cannot be judged at 100%. My 645D sensor is 33x44mm, do you really think you can judge acceptable sharpness (a technical criteria based on CoC) by looking at a 9mm x 5mm section of the sensor on a 24" monitor, because that is what a 100% view is with a 645D. So as pixel resolution has increased, photographers have been judging images from higher and higher magnifications. Put a microscope on a piece of film and you can see the grain, but you cannot judge image sharpness.
I am sorry, but the theories involving diffraction limit have not changed. Diffraction limit and DoF is not impacted by pixel pitch. It never has. This myth has come from pixel peeping and really not understanding how images are perceived.
BTW, it is not more difficult to focus with a camera with 12MP as it is with 36MP (the focal plane is the focal plane and DoF is not changing). If your lenses create a sharp on a 12MP camera, the images from a 36MP camera will look just as sharp with the same lens--dividing an image into more pixels does not cause an image to be softer. You may be more more aware of the shortcomings at 100% monitor view, but that is not a real viewing condition--look at an image at 200% if you want to see the image softer or 50% if you want to see it sharper.
Here is a paper on depth of field by Zeiss.
http://www.zeiss.com/c12567a8003b8b6f/embedtitelintern/cln_35_bokeh_en/$file/cln35_bokeh_en.pdf