Originally posted by Bill_R Check out the Raynox Macro Club thread
https://www.pentaxforums.com/forums/lens-clubs/74221-raynox-macro-club.html
I think you'll find the recommendation is to use the 150 with the DA 55-300 and the 250 with lower focal lengths such as the DA 18-55.
That thread has heaps of useful info but it's quite long and takes a while to go through - well worth it though, you'll be hooked before you start.
The Raynox 250 (125mm or 8 diopters) is stronger than the Raynox 150 (208mm or 4.8 diopters); the relative strength is 208/125 = 1.66x.
For the same sized image the 150 will be 1.66x further from the subject. That extra distance is important as it makes it easier to get light on the subject, manipulate the subject, and avoid scaring bugs away. But the 150 is enough weaker than the 250 that you need to put it onto a longer focal length lens to get the same magnification as the 250 on a shorter lens.
The formula for magnification when a close-up lens is put on a primary lens is:
mag = (primary.focal.length)/(close-up.focal.length)
The Raynox 150 on a 300mm lens has a magnification of about 1.5x which is about the limit of what most people can hand-hold.
I think the Raynox 150 is the best compromise if you have a 300mm lens; the Raynox 250 might be best if you intend to use a primary lens much shorter than 200mm.
I've never seen anybody say there's a difference in image quality between the two Raynox lenses.
The main reason I suggested the DA(L)55-300/Raynox DCR150 combination with your kit lens is that combination covers a huge range of hand-held photographic possibilities (including the maximum practical hand-held distance for telephotos of wildlife etc).
I think the Raynox DCR 250 coupled with the same two primary lenses would be less versatile in the field because of the 250's shorter working distance and your probable inability to hand hold it at higher magnifications.