Originally posted by Grey Area Question about self-clean though - I have "on startup" and "on shutdown" options. Currently turned both on. Is it safe to leave them on or does it reduce the life of the sensor?
I have mine set to run on startup. I have done that on all cameras since the k-x with no issues. Why they do not have it set as on being the default I have no idea. You are certainly not the first (or the 100th) person to post here with the same issue. On older models the dust removal was not as good (or non-existent) so we often struggled with physically cleaning the sensor. But since the k-5 the system has gotten really good. So good that I have never done a physical cleaning of any camera since the k-5.
However, due caution is always advised, try to change lenses with the camera pointed down. Don't change lenses in adverse environments. Dust is easy to clean either with the camera DR system or with a rocket blower, but sticky pollen and other stuff is not so easy and requires a wet cleaning.
In short, take as much care as you can, leave the DR system on at startup, and if the worst happens understand how to physically clean the sensor.