Remove the TTL prism and inspect the 2 connection tangs on the base.
Likewise inspect and clean if necessary the contacts on the base of the camera where the focusing screen is.
If your version of the meter has an on/off switch, are you turning this on to activate the meter? It may sound a silly question, but it can be quite surprising how new users of this camera assume the meter will turn on by itself the moment the camera is picked up!
Failing the above and any change to a higher ISO as a sort of 'jolt' to its system, age-related derangement of the meter is a possibility. This is very common in the
older 6x7 / Asahi Pentax meters of the late 1960s. Most people just source a replacement TTL prism, of which there are plenty available (but should be astutely checked for operation and with clear pathways for return if something is not quite kosher). The electronics within the TTL meter are very rudimentary, and would suit somebody skilled in electronics who can find their way around and inspect/calibrate the meter to working order.
Age will catch up with the meters and the cameras eventually.
When these things first came out, the glowing red and orange valves in radios were attractive to moths and little kids like me yet to be made aware of the danger of poking and pulling valves while they were powered by electricity...