Depth-of-field, focal length and aperture have a very fixed relationship.
To make for easy numbers, if the depth of field of a lens at f/4 is 1ft. at 10ft., it'll still be 1ft at 15ft. with a 1.5x adaptor, or 1ft at 20ft with a 2x adaptor, assuming the aperture setting isn't adjusted.
Obviously, there will be light loss due to the converter, so something will have to change to maintain exposure.
If the depth of field is to be maintained, either the ISO will need to be increased, the shutter speed decreased, or a combination of both.
It'll be a personal decision at exposure time to choose which option to take … give thanks for SR and pray for good light … a monopod or tripod might help