Originally posted by NecroticSoldier would you rather use a slower shutter speed and try and get by with it or bumping the ISO up to 6400+ or... not shoot it at all?
If that's the only options, take the shot with the higher ISO. What do you have to lose? You can process out noise. Good luck processing a blurred image.
Or, try both and see which works best.
Process the noise as best as possible, or lower the ISO and under-expose it, then correct it in photoshop (which will also lead to noise processing). Maybe you'll end up with a usable image.