Possibly, if I remember right you do a lot of work with very wide apertures? That's where the small differences will show. On lenses @ f/5.6 or so it is very hard to see that any AF fine tuning will help. The wider DOF masks any small error. And there are many other possible causes of 'softness' such as subject motion, camera motion, lens just being soft wide open.
I would only consider messing with AF fine tuning if you can repeatedly duplicate the softness in a controlled test. On a tripod, well lit focusing target using time delay or remote release. It is very easy to make things worse as in most cases the margin of error in the test exceeds the original AF error.
Also, on manual lenses the 'green hex' and 'in focus beep' are not really reliable beyond f/5.6 or maybe f/4. After that the DOF is smaller than the range of in focus indication ( if that makes sense).
If you really feel you need to tune each lens then you might consider moving up to a camera that allows that such as k-5 or k-3. I think the k-50 does as well but I'm not 100% sure on that.
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