If you like light weight and acceptable images on an APSc camera, the DA/DC/etc. class lenses will do fine. If you want really good images on an APSc camera buy the better APSc glass (DA*, pro/ better quality Siggies and Tamrons, or Zeiss with MF). I was a diehard DA* user and defender. At issue were the 4 motors I put in a 16-50 DA* (albeit with very heavy commercial level usage). My wife's "pry my cold dead hands off it" lens is the DA 18-270. She is a well published and award winning pic taker, and for other than long critters, her go to lens. Before that it was the 18-250, not as good a build. DA*s are GREAT lenses, as are the limiteds...
On FF on APSc, I had heavy CA on a FA 85 f1.4, some on F300 F4.5 and a bit on FA*300 F2.8. My wife has little issue with her Siggy 150-500 DG (GEN2, a key difference). Well controlled lens, and FF. I recently switched to the DFA Trio (15-30, 24-70, 70-200 DA*) and have been using the DA 150-450 on a K3 for years. I switched for 2 reasons, build quality and newer coatings, both helpful in the field. Backpack weight went up 2 lbs across the 3 lower range and the DA solution. This is MORE TO LUG. I got 1/2 stop from 135-200mm (F2.8 vs F4), important in what I shoot. Newer coatings perform better, better controlled flare and CA. Have the option for FF if I want a different DoF profile, but due to wildlife, I'm a dedicated APSc shooter. Yes, a tiny bit more crisp at the edges, less vignetting in the corners with wider glass...
No downside to FF on APSc, except weight and cost, older ones will show more CA (even GREAT lenses), upside is bigger apertures (depending on the solution), maybe better on edges and in the corners. Like Norm said, just a smaller image from the center...
Last edited by GlassJunkie; 06-14-2017 at 08:34 AM.