I have a 5D and I've used the K5 for 2yrs.
The K5 is superior in every way except shallower DOF type shots.
Interface, the 5D is clunky and not well thought out imo. (no auto iso; 2ev bracketing only; no 3s timer; lousy info "at a glance" in both LCD and viewfinder; antiquated AF)
Larger viewfinder, yes, but I MF without issues on the K5.
As a system, Canon is larger and heavier.
The 5d isn't that heavy by itself, but it is with some of the lenses. (though the cheapy f1.8 plastic fantastics are 'weightless')
The nice thing about FF is how the fast 50mm, 'transforms' into a very versatile lens that gives shallow DOF type shots be it portrait (head, half body, full body).
Very nice for environmental portraits with a shallow DOF if you are into this sort of shots.
The 85mm also transforms to a very usable FL indoors.
Once you stop down (eg. landscapes; macros; or for more DOF)the FF advantage is taken away, the K5 is far better. (ISO; usability; megapix for large printing or cropping; fine grain; DR; AF, etc)
My advice is that if you crave the 'shallow DOF look', try one.
It won't replace the K5 if you are thinking in that direction.
12mp is pretty fine imho, and the 5d is still an able (though antiquated) camera (and so are film cameras
)
my few cents.
(BTW, I only use MF M42 lenses on the 5D; don't believe in investing in the Canon system)