My daughter and I have used the AF280T on several cameras and in several situations, with excellent results - off camera or on, usually with it set in Auto mode. But we've set aperture and shutter speed manually.
So I figured I'd try it with the Program Plus - it reads ASA from camera, and feeds back the correct aperture and shutter, which the camera then sets. No TTL with the Program plus, but it works great.
Then, I wondered what would the K100D do in Program mode, with the AF280T attached? Wonder of wonders, the flash reads ASA from K100D and instructs K100D to set aperture and shutter... except the K100D also adjusts shutter between 50 and 180 depending on ambient light.
I didn't know this. The AF280T (and the AF200T) work in dedicated mode with the K100D, not TTL but well enough.
Examples (these are from my daughter's stream, though I took them):
indoors, shutter set to 1/60:
Outside, shutter set to 1/180, f/8... without flash the camera would have selected f/6.3 at 1/180.