G'Day John,
Just thought I'd drop you a line to let you know about an NR thread that you might be interested in.
Mike (Big Mack Cam) started a conversation on NR in various software to compare it to his experience and output from LR. I've added several posts using NR in On1 and thought some of the points discussed might contribute to the work you're doing.
The thread can be found here:
Let's compare High ISO noise reduction in post-processing software? - PentaxForums.com
Regards,
Tas