Originally posted by rparmar If you are this concerned about ultimate detail then buying into a system with a smaller sensor than APS-C was really the wrong move. Better to get a Nikon D700. Or better yet, a Pentax 645D. These can resolve detail no smaller sensor possibly can. Results I have seen with the 645D are exactly what one would expect of medium format -- stunning.
It's not all about sharpness; more important is acuity.
I have been using the 5D (12MP) and E-3 (10MP) for several years and there are advantages to both in terms of IQ. With good light the high pixel density of the E-3 gives me more detail than the 5D. The 5D however gives me cleaner files and a more pleasing image "most" of the time.
I am not necessarily interested in ultimate detail as I am sharpness. As pixel density increases (and Pentax is going to increase it) then the shortcomings of the lenses will become more and more apparent.
Photozone ran two reviews of the Sigma 50mm f/1.4. One on an 8MP 350D and one one the 15MP 50D. The higher pixel density really challenged the Sigma lens.
"It's quite obvious that the lens has more trouble with the 15mp of the EOS 50D compared to our initial test based on the EOS 350D @ 8mp."
Sharpness plays a big role in how much an image "pops" and how how well a lens isolates the subject from the background. While the smaller APS-C sensor may not give you the shallow DoF of the full-frame, but with a really sharp lens (good focus), with great bokeh, you can achieve very good subject isolation.
Because I like a larger aperture to keep ISO down, improve subject isolation, and keep shutter speed up I am very critical of how a lens performs wide open. If I shot landscapes or macro I would be less critical of this, and less critical of the Limited lenses.